Redefining skin regeneration

Longevity and regenerative medicine are closely aligned research fields, both striving to extend the vitality and functionality of human tissues and even organs. These science disciplines are revolutionising how we think about health, aging, and innovation.

Advances in science are rapidly transforming healthcare, with therapies that not only repair damaged tissues but also harness the body’s intrinsic ability to heal and regenerate. These breakthroughs are offering solutions for conditions previously considered untreatable.

Linio Biotech’s field is regenerative aesthetics. This is an emerging subfield of regenerative medicine that applies these principles to skin treatments and soft tissue restoration. By leveraging the body’s innate regenerative potential, regenerative aesthetics is revolutionising approaches to skin rejuvenation, scar repair, and volume restoration. This approach offers enhanced outcomes compared to traditional methods, leading to significant improvements in skin texture, elasticity, and overall quality, providing long-lasting, natural-looking results.

Linio Biotech is at the forefront of this revolution, challenging the status quo in bioregenerative treatments. Current autologous methods, such as platelet-rich plasma (PRP) therapy, nanofat and microfat grafting often require complex and invasive procedures. Linio Biotech is reimagining these approaches by introducing scientifically validated, ready-to-use tissue innovations that simplify and enhance outcomes for both patients and practitioners.

With a strong foundation in Tience® technology and a commitment to advancing the latest breakthroughs in regenerative medicine, Linio Biotech is setting a new standard in the field. Our technology is designed to be safe, sustainable, and accessible, offering healthcare professionals and patients a paradigm shift in how damaged skin and soft tissue deficiencies are treated. By supporting natural regeneration, Linio Biotech not only improves clinical outcomes but also empowers more patients to treat skin defects and problems related to skin aging.

In the early 2000s, regenerative medicine experienced a breakthrough. As fat grafting became more widespread, researchers observed an unexpected and remarkable effect of adipose tissue on skin health. Initially, this discovery was incidental: skin damage in treated areas, such as scars, healed significantly faster, improving both in appearance and function. The true breakthrough, however, came when fat grafting was applied to the face. Aging skin showed visible improvements in tone, texture, and elasticity—seemingly without effort.

Since then, the unique regenerative properties of adipose tissue have been extensively studied by research teams worldwide. While the findings are revolutionary, fat grafting has clear limitations: the procedure is invasive, costly, and must be performed in operating rooms. Additionally, adipose tissue cannot be transferred between individuals, restricting its accessibility.

So, what gives adipose tissue its regenerative power? Studies show that its unique ability to heal and rejuvenate skin lies in its bioactive components. These components function as a "first-response unit" within the skin, accelerating healing processes and guiding the development of new, healthy tissue.

Linio Biotech has dedicated over 15 years to answering a bold question: Can the skin-repairing bioactive components of adipose tissue be isolated without the fat cells and developed into a treatment accessible to everyone? After years of rigorous research, we achieved what was once thought impossible: isolating the regenerative power of adipose tissue and transforming it into a ready-to-use product.

The result is Tience®, a category defining innovation that represents a major milestone in tissue science and technology.

Tience® is designed to revolutionize regenerative skin treatments by delivering the benefits of adipose tissue in a safe, accessible, and efficient form—without the need for invasive procedures. With Tience®, Linio Biotech is redefining the future of regenerative aesthetics, offering a scientifically advanced solution for skin healing and rejuvenation that is poised to set a new standard in the field.